22 November 2018: software updates on our old server have inactivated some services. We are actively seeking to get these up and running over the next four months. Some services are provided via alternative links shown below
Discovery @ Bioware

This server contains several tools for short linear motif (SLiM) discovery, peptide characterisation and related analyses of proteomics data.

SLiMs are short (2-12 amino acids) and often redundant, so methods need to allow for chance findings and calculate how likely enrichments are (significance). SLiMs are typically intracellular and often found in unstructured (disordered) protein regions. SLiMs can play roles in protein binding, cleavage, modification and transport (see ELM). Bioactive peptides are typically derived from extracellular proteins.

The tools are hosted by the Shields' Lab, Conway Institute of Biomolecular and Biomedical Research and and UCD Centre for Bioinformatics. Tools are developed in conjuction with Rich Edward's Lab (University of New South Wales) and Norman Davey's lab (currently at UCD shortly moving to London).