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Output Description
An example results output for a Dynein Light Chain binding protein dataset is available here
Example Visualisations
The Concise Motif Map trys to condense all the attributes of a protein into one graphic. All protein features masked in the dataset are overlayed on to the protein.
Red for proteins , green for fold , khaki for transmembrane , pink for tissue or
location. All other masked features are grey and labelled.Graphs for Net charge
, Hydropathy and absolute charge are plotted above the protein and
graphs for disorder ( using IUPRED) and surface accessibility (using the Emini method)
are graphed below the protein. The top twenty motifs are placed along the protein as
coloured balls with their rank contained in the centre of the ball. THese balls are
placed so if the case arises that two or more motifs overlap the the highest ranking
motif will be placed on top. Also non-overlapping lollipops decend from the motif ball
to give the actual motif sequence.
The Motif alignment for the 30 residues either side of the motif takes a motif and the stacks each protein containing that motif on top of each other.
The alignment contains the 30 residues on either side of the sequence. The alignments are ungapped and are not aligned in terms of a multiple algnment. This alignment will help
the user to understand the context of the motif and allow a visualisation of any obvious homology between sequences around the motif which would give information about whether
a motif is convergently or divergently evolved
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