Description
Home of the datasets used during the Relative Local Conservation (RLC) masking analyses
Links
Reference
Tools
Data
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Aligments
Download Gopher generated ortholog alignments used in the analyses
Complete human zipped (~23,000 alignments 80.6mb)
Datasets
Benchmarking set of 20 proteins-protein interaction datasets where a subset of interactions are known to be mediated by SLiMs from HPRD.
Complete zipped (492kb)
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Benchmarking set of 16 ELM containing datasets from ELM.
Each protein in each dataset has at least one instance of a known functional SLiM
Complete zipped (108kb)
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Visualisation
RLC plotter
Tool for viewing relative conservation of a protein (Uniprot Human only).Motifs can also be ploted on to graph
Interesting examples
Collagen linkTrimeric repeat G-X-Y with highly conserved glysine causing sawtooth pattern.
Epsin 2 link 6 repeats of a clathrin binding [DE]PW (1st instance marked) evenly spaced over 100 residues.
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Motif Context Visualiser website
Another tool for viewing relative conservation of a protein, along with user defined distributions, regions, motifs and RE matches.
Using the following file format link. Giving an output like this link
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