Disintegrin and metalloproteinase domain-containing protein 22 (ADAM22)
AlignmentMotifsModificationSwitchesStructureMutationIsoformsSNPsFeaturesDisorder

 
|792
|842
|871
RSNSWQ
V
S
T
N
S
A
S
S
S
K
K
R
S
N
G
L
S
H
S
W
S
E
R
I
P
D
T
K
H
I
S
D
I
C
E
N
G
R
P
R
S
N
S
W
Q
G
N
L
G
G
N
K
K
K
I
R
G
K
R
F
R
P
R
S
N
S
T
E
T
L
S
P
A
K
S
P
S
S
S
T
V
S
T
N
S
A
S
S
S
K
K
R
S
N
G
L
S
H
S
W
S
E
R
I
P
D
T
K
H
I
S
D
I
C
E
N
G
R
P
R
S
N
S
W
Q
G
N
L
G
G
N
K
K
K
I
R
G
K
R
F
R
P
R
S
N
S
T
E
T
L
S
P
A
K
S
P
S
S
S
T
V
S
T
N
S
A
S
S
S
K
K
R
S
N
G
L
S
H
S
W
S
E
R
I
P
D
T
K
H
I
S
D
I
C
E
N
G
R
P
R
S
N
S
W
Q
G
N
L
G
G
N
K
K
K
I
R
G
K
R
F
R
P
R
S
N
S
T
E
T
L
S
P
A
K
S
P
S
S
S
T
G
S
T
N
S
A
S
S
S
K
K
R
S
N
G
L
S
H
S
W
S
E
R
I
P
D
T
K
H
I
S
D
I
C
E
N
G
R
P
R
S
N
S
W
Q
G
N
M
G
G
N
K
K
K
I
R
G
K
R
F
R
P
R
S
N
S
T
E
T
L
S
P
A
K
S
P
S
S
S
T
V
S
T
N
S
A
S
S
S
K
K
R
S
N
G
L
S
H
S
W
S
E
R
I
P
D
T
K
H
I
S
D
I
C
E
N
G
R
P
R
S
N
S
W
Q
G
N
L
G
G
N
R
K
K
V
R
G
K
R
F
R
P
R
S
N
S
T
E
T
L
S
P
A
K
S
P
S
S
S
T
V
S
T
N
S
A
S
S
S
K
K
R
S
N
G
L
S
H
S
W
S
E
R
I
P
D
T
K
H
I
S
D
I
C
E
N
G
R
P
R
S
N
S
W
Q
G
N
I
G
G
N
R
K
K
V
R
G
K
R
F
R
P
R
S
N
S
T
E
T
L
S
P
A
K
S
P
S
S
S
T
V
S
S
N
S
A
S
S
S
K
k
r
S
N
G
L
S
H
S
W
S
E
R
I
P
D
T
K
H
V
S
D
V
C
E
N
G
R
P
R
S
N
S
W
Q
G
N
V
S
S
S
R
K
K
L
R
G
K
R
F
R
P
R
S
N
S
T
E
T
L
S
P
A
K
S
P
S
S
S
T
V
S
S
N
S
G
S
S
S
K
K
R
S
N
G
L
S
H
S
W
S
E
R
I
P
D
A
K
H
I
S
D
V
C
E
N
G
R
P
R
S
N
S
W
Q
G
N
I
T
G
T
R
K
K
L
K
G
K
K
F
R
A
R
S
N
S
T
E
T
L
S
P
A
K
S
P
T
S
S
T
V
S
D
S
R
A
R
S
R
K
K
R
S
N
G
L
S
H
S
W
S
E
R
I
P
D
T
K
H
I
S
D
I
C
E
N
G
R
P
R
S
N
S
W
Q
G
N
L
G
G
N
R
K
K
I
R
G
K
R
F
R
P
R
S
N
S
T
E
T
L
S
P
A
K
S
P
S
S
S
T
 
 
 
 
 
In isoform 2, isoform 4 and isoform 5.
In isoform 2.
In isoform 3 and isoform 4.
Disintegrin and metalloproteinase domain-containing protein 22
Cytoplasmic
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

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