Epsin-2 (Epn2)
AlignmentMotifsModificationSwitchesStructureMutationIsoformsSNPsFeaturesDisorder

 
|454
|504
|533
LNPFL
S
A
S
S
K
P
S
S
A
R
K
T
P
E
S
F
L
G
P
N
A
A
L
V
N
L
D
S
L
V
T
K
P
A
P
P
A
Q
S
L
N
P
F
L
A
P
G
A
A
A
P
A
P
V
N
P
F
Q
V
N
Q
P
Q
P
L
T
L
N
Q
L
R
G
S
P
V
L
G
S
S
A
S
A
S
S
K
P
S
S
A
R
K
T
P
E
S
F
L
G
P
N
A
A
L
V
N
L
D
S
L
V
T
K
P
N
P
P
A
Q
S
L
N
P
F
L
A
P
G
A
A
A
P
A
P
V
N
P
F
Q
V
N
Q
P
Q
P
L
T
L
N
Q
L
R
G
S
P
V
L
G
S
S
A
V
A
S
S
K
P
S
S
A
R
K
T
P
E
S
F
L
G
P
N
A
A
L
V
N
L
D
S
L
V
T
R
P
A
P
P
A
Q
S
L
N
P
F
L
A
P
G
A
P
a
s
A
P
V
N
P
F
Q
V
N
Q
P
Q
P
L
T
L
N
Q
L
R
G
S
P
V
L
G
T
S
T
V
A
S
S
K
P
S
G
A
R
K
T
P
E
S
F
L
G
P
N
A
A
L
V
N
L
D
S
L
V
T
R
P
A
P
P
A
Q
A
L
N
P
F
L
A
P
G
A
A
t
s
A
P
V
N
P
F
Q
V
N
Q
P
Q
P
L
T
L
N
Q
L
R
G
S
P
V
L
G
G
S
A
L
V
S
S
K
Q
S
V
A
R
K
T
P
E
S
F
L
G
P
N
A
A
L
V
N
L
D
S
L
I
T
K
P
S
Q
P
V
P
S
L
N
P
F
L
A
P
G
S
S
t
p
T
P
V
N
P
F
Q
V
N
Q
P
Q
P
L
T
L
N
Q
M
R
A
S
P
I
M
G
T
S
P
V
T
S
S
K
Q
T
S
V
R
K
T
P
E
S
F
L
G
S
N
A
A
L
V
N
L
E
T
L
V
S
M
P
P
P
A
A
P
I
L
N
P
F
L
A
s
a
T
T
t
t
P
P
V
N
P
F
Q
V
N
Q
P
Q
A
L
T
L
N
Q
L
R
S
S
P
M
M
g
g
A
E
S
G
-
-
-
-
-
P
T
R
K
T
P
E
S
F
L
G
P
N
A
A
L
V
N
L
D
S
L
V
S
K
P
L
Q
Q
A
P
V
S
N
P
F
L
A
g
g
V
a
p
p
A
p
v
N
P
F
Q
V
N
Q
P
Q
P
P
T
L
N
Q
M
R
V
S
P
M
M
g
s
A
Q
M
T
S
G
K
Q
S
A
A
R
K
T
P
E
S
F
L
G
P
N
A
A
L
V
N
L
D
S
L
V
S
K
P
P
Q
P
V
T
S
L
N
P
F
L
A
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
S
m
p
S
T
G
A
T
A
k
k
D
A
H
S
F
L
G
E
N
S
A
L
V
N
L
D
N
L
I
K
P
I
A
P
Q
T
Q
T
g
n
P
F
-
-
S
-
-
-
d
v
V
p
t
N
L
F
Q
Q
Q
Q
P
A
V
P
S
I
N
Q
L
K
q
a
P
V
M
g
v
S
T
G
i
e
T
L
P
T
S
T
g
k
T
P
Q
S
F
L
G
E
N
S
A
L
V
N
L
D
N
L
V
S
S
S
A
-
-
I
K
S
T
T
P
T
-
-
P
-
A
A
t
s
Y
S
A
N
P
F
A
T
a
a
P
P
R
P
T
I
N
Q
I
R
Q
D
P
W
-
-
-
-
-
I
n
n
N
S
T
N
G
T
R
K
T
P
E
N
F
L
G
E
N
S
N
L
V
N
L
D
N
L
L
G
S
G
T
P
S
T
T
G
G
N
P
F
L
T
-
G
A
A
-
P
A
N
A
N
P
F
A
A
Q
Q
R
K
S
P
T
L
N
E
M
R
A
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
Epsin-2
1
2
3 X 3 AA repeats of N-P-F
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Powered by ProViz
hover over features for details