Transcription factor HES-1 (HES1)
AlignmentMotifsModificationSwitchesStructureMutationIsoformsSNPsFeaturesDisorder

 
|236
|280
WRPWRN
G
A
F
A
H
S
G
P
V
I
P
V
Y
T
S
N
S
G
T
S
V
G
P
N
A
V
S
P
S
S
G
P
S
L
T
A
D
S
M
W
R
P
W
R
N
G
A
F
A
H
S
G
P
V
I
P
V
Y
T
S
N
S
G
T
S
V
G
P
N
A
V
S
P
S
S
G
P
S
L
T
A
D
S
M
W
R
P
W
R
N
G
A
F
A
H
S
G
P
V
I
P
V
Y
T
S
N
S
G
T
S
V
G
P
N
A
V
S
P
S
S
G
P
S
L
T
A
D
S
M
W
R
P
W
R
N
G
A
F
A
H
S
G
P
V
I
P
V
Y
T
S
N
S
G
T
S
V
G
P
N
A
V
S
P
S
S
G
P
S
L
T
A
D
S
M
W
R
P
W
R
N
G
A
F
A
H
S
G
P
V
I
P
V
Y
T
S
N
S
G
T
S
V
G
P
N
A
V
S
P
S
S
G
S
S
L
T
S
D
S
M
W
R
P
W
R
N
P
A
F
P
H
N
G
S
V
I
P
V
Y
T
N
s
v
G
T
A
L
P
P
S
-
V
S
P
S
V
M
P
S
V
T
A
D
S
V
W
R
P
W
-
-
A
A
F
A
P
N
G
P
V
I
P
V
Y
A
N
N
S
N
T
P
V
-
P
V
A
V
S
P
-
G
A
P
S
V
T
S
D
S
V
W
R
P
W
-
-
P
A
F
P
P
g
g
P
V
I
P
L
Y
A
N
a
s
S
E
R
V
h
p
A
g
a
S
Q
A
G
S
p
a
E
R
R
E
A
V
W
R
P
W
-
-
P
A
F
G
P
g
g
S
L
L
P
T
Y
P
S
A
-
-
A
A
A
G
-
-
-
-
-
-
-
G
G
P
-
-
-
-
-
-
-
-
-
-
-
-
-
G
A
K
a
t
s
m
p
l
I
P
I
P
Q
R
T
A
S
T
A
S
a
s
S
s
s
P
P
L
Q
K
p
a
L
V
M
r
e
v
w
R
P
W
-
-
-
C
Y
S
-
-
P
P
-
T
P
-
H
T
S
S
S
D
S
G
V
W
S
S
G
S
S
P
p
g
K
P
-
F
N
N
q
t
V
W
R
P
W
G
L
Q
Q
L
A
-
-
-
-
Q
L
S
M
Y
T
Q
L
F
N
N
P
A
g
p
-
-
L
R
A
D
A
G
v
a
Q
S
P
e
k
I
E
D
R
S
R
V
WRPW motif
Transcription factor HES-1
Pro-rich
Ser/Thr-rich
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

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