Spindle assembly checkpoint component MAD3 (MAD3)
AlignmentMotifsModificationSwitchesStructureMutationIsoformsSNPsFeaturesDisorder

offset
Motif of interest
ELM
mutagenesis site
pfam
secondary structure ( + details )
PDB
chain
 
|339
|389
|418
EFSLEEVLA
G
R
S
D
P
V
Y
Q
M
I
N
T
K
D
Q
K
P
E
K
I
D
C
N
F
K
L
I
Y
C
E
D
E
E
S
K
G
G
R
L
E
F
S
L
E
E
V
L
A
I
S
R
N
V
Y
K
R
V
R
T
N
R
K
H
P
R
E
A
N
L
G
Q
E
E
S
A
N
Q
K
E
A
E
V
P
C
P
-
-
-
-
-
-
-
-
-
-
-
-
M
P
S
F
T
P
Y
V
E
E
S
A
Q
Q
Q
V
M
T
P
C
K
I
E
P
S
I
N
-
-
-
-
-
H
V
L
S
A
R
K
P
E
K
E
E
D
P
L
R
R
V
Q
N
H
H
Q
D
T
Q
E
K
K
e
e
A
R
T
F
G
-
-
E
R
S
V
S
R
L
P
S
K
P
K
E
E
V
P
H
A
E
E
F
L
d
p
S
P
K
S
P
G
D
F
T
S
A
A
q
a
K
Q
C
T
Q
A
T
L
D
S
C
E
E
N
M
V
V
P
S
R
D
G
K
F
S
P
I
Q
E
K
S
P
K
q
c
H
P
K
L
T
-
-
-
-
-
V
F
R
E
V
Q
V
P
K
S
D
K
K
N
E
R
I
S
I
D
M
D
L
L
Y
D
G
G
I
E
F
C
L
E
E
V
Y
A
K
S
R
G
L
Y
G
K
K
Y
N
A
R
P
A
T
P
K
A
K
T
T
T
I
M
V
K
D
S
S
p
-
V
A
V
P
P
-
-
-
-
-
-
-
-
-
-
-
P
K
P
S
F
Q
P
F
V
E
E
D
D
Q
P
P
A
V
T
P
C
K
I
N
P
A
V
N
-
-
-
-
-
-
-
-
-
-
-
S
V
L
S
A
R
K
P
S
R
L
E
Q
T
P
L
K
K
L
Q
E
K
Q
M
-
Spindle assembly checkpoint component MAD3
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Powered by ProViz
hover over features for details