Thrombopoietin (THPO)
AlignmentMotifsModificationSwitchesStructureMutationIsoformsSNPsFeaturesDisorder

 
|157
|207
|236
PNRTSG
R
G
K
V
R
F
L
M
L
V
G
G
S
T
L
C
V
R
R
A
P
P
T
T
A
V
P
S
R
T
S
L
V
L
T
L
N
E
L
P
N
R
T
S
G
L
L
E
T
N
F
T
A
S
A
R
T
T
G
S
G
L
L
K
W
Q
Q
G
F
R
A
K
I
P
G
L
L
N
Q
T
R
G
K
V
R
F
L
M
L
V
G
G
S
T
L
C
V
R
R
A
P
P
T
T
A
V
P
S
R
T
S
L
V
L
T
L
N
E
L
P
N
R
T
S
G
L
L
E
T
N
F
T
A
S
A
R
T
T
G
S
G
L
L
K
R
Q
Q
G
F
R
A
K
I
P
G
L
L
N
Q
T
R
G
K
V
R
F
L
L
L
V
V
G
P
S
L
C
A
K
R
A
P
P
A
T
A
V
P
G
S
I
S
P
L
L
T
L
N
K
L
P
N
R
T
S
G
L
L
E
T
N
S
S
V
S
A
R
T
T
G
F
G
L
P
N
R
L
Q
G
F
R
A
K
I
P
G
L
L
N
Q
T
R
G
K
V
R
F
L
L
L
V
E
G
P
T
L
C
V
R
R
T
L
P
T
T
A
V
P
S
S
T
S
Q
L
L
T
L
N
K
F
P
N
R
T
S
G
L
L
E
T
N
F
S
V
T
A
R
T
A
G
P
G
L
L
S
R
L
Q
G
F
R
V
K
i
p
G
Q
L
N
Q
T
R
G
K
V
R
F
L
L
H
A
V
R
P
L
L
C
A
R
Q
D
Q
M
A
T
A
A
T
G
s
t
P
S
V
R
T
T
S
E
L
K
D
K
T
P
T
S
L
E
S
G
P
G
S
S
A
R
A
T
G
t
t
T
S
R
P
L
T
K
S
P
V
R
I
P
G
L
L
N
H
T
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
G
L
-
-
-
-
In isoform 3.
Thrombopoietin
O-linked (GalNAc...)
O-linked (GalNAc...)
O-linked (GalNAc...)
N-linked (GlcNAc...) (complex)
N-linked (GlcNAc...) (complex)
O-linked (GalNAc...)
N-linked (GlcNAc...) (complex)
disulfide bond
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

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