Complement component C8 beta chain (C8B)
AlignmentMotifsModificationSwitchesStructureMutationIsoformsSNPsFeaturesDisorder

 
|512
|562
|591
WSNW
G
V
P
V
L
K
G
S
R
C
D
C
I
C
P
V
G
S
Q
G
L
A
C
E
V
S
Y
R
K
N
T
P
I
D
G
K
W
N
C
W
S
N
W
S
S
C
S
G
R
R
K
T
R
Q
R
Q
C
N
N
P
P
P
Q
N
G
G
S
P
C
S
G
P
A
S
E
T
L
D
C
S
G
V
P
V
L
K
G
S
R
C
D
C
I
C
P
V
G
S
Q
G
L
A
C
E
V
S
Y
R
K
N
I
P
I
D
G
K
W
N
C
W
S
N
W
S
S
C
S
G
R
R
K
T
R
Q
R
Q
C
N
N
P
P
P
Q
N
G
G
S
P
C
S
G
P
A
S
E
T
L
D
C
S
G
V
P
V
L
K
G
S
R
C
D
C
I
C
P
V
G
S
Q
G
L
A
C
E
V
S
Y
W
K
N
I
P
I
D
G
K
W
N
C
W
S
N
W
S
S
C
S
G
R
R
K
T
R
Q
R
Q
C
N
N
P
P
P
Q
N
G
G
S
P
C
S
G
P
A
S
E
T
L
D
C
S
G
V
P
V
L
K
G
T
R
C
E
C
I
C
P
A
G
F
Q
G
S
A
C
E
V
T
H
R
K
N
V
P
I
D
G
K
W
N
C
W
S
N
W
S
P
C
S
G
G
H
K
T
R
Q
R
Q
C
T
N
P
P
P
G
N
G
G
N
P
C
S
G
P
A
S
E
T
L
N
C
-
G
V
P
V
L
K
G
S
R
C
E
C
I
C
P
G
G
F
Q
G
T
A
C
E
V
T
Y
R
K
D
I
P
I
D
G
K
W
S
C
W
S
D
W
S
A
C
S
G
G
H
K
T
R
H
R
Q
C
N
N
P
A
P
H
K
G
G
S
P
C
S
G
P
A
S
E
T
L
N
C
-
G
I
P
V
L
K
G
T
H
C
E
C
I
C
P
L
S
R
R
G
T
A
C
E
T
P
S
R
T
D
A
A
I
N
G
N
W
G
C
W
A
S
W
S
P
C
S
G
G
Q
R
T
R
R
R
Q
C
N
N
P
T
P
Q
N
G
G
S
S
C
S
G
P
D
A
E
T
V
T
C
-
G
L
A
V
F
I
E
N
R
C
E
C
I
C
P
L
G
F
T
G
M
A
C
E
I
T
K
R
P
V
N
V
I
D
G
S
W
S
C
W
S
S
W
T
P
C
S
R
R
I
Q
T
R
D
R
Q
C
N
N
P
S
P
Q
N
G
G
N
Q
C
E
G
T
N
T
D
T
R
N
C
-
G
L
A
V
L
K
G
M
R
C
T
C
I
C
P
A
G
V
K
G
V
S
C
E
I
T
Q
R
K
G
L
A
I
D
G
N
W
S
C
W
S
S
W
S
S
C
S
G
K
I
Q
H
R
T
R
Q
C
N
N
P
A
P
H
N
G
G
V
A
C
A
G
A
Q
E
E
S
A
D
C
V
G
F
P
I
I
R
D
S
Y
C
E
C
L
C
G
M
G
T
C
G
I
S
C
E
L
G
T
S
E
G
-
D
A
T
G
S
W
S
C
W
T
S
W
T
E
C
I
E
A
K
Q
K
R
E
R
L
C
N
S
P
I
P
G
S
I
K
T
-
C
P
G
R
Q
K
E
E
T
S
C
-
A
A
K
I
v
n
G
K
T
C
T
C
L
C
K
F
P
Y
T
G
V
D
C
H
N
E
T
G
N
l
k
P
F
N
G
Q
w
s
S
W
G
S
W
S
S
C
s
g
G
T
R
Y
R
T
R
Y
V
T
R
-
Y
P
K
N
G
G
S
G
C
P
G
L
T
W
-
T
T
G
C
-
Complement component C8 beta chain
EGF-like
TSP type-1 2
C-linked (Man)
C-linked (Man)
disulfide bond
disulfide bond
disulfide bond
disulfide bond
disulfide bond
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

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