Transcription factor E2F3 (E2F3)
AlignmentMotifsModificationSwitchesStructureMutationIsoformsSNPsFeaturesDisorder

 
|95
|145
|174
RRLEL
A
G
S
L
L
Y
T
T
P
H
G
P
S
S
R
A
G
L
L
Q
Q
P
P
A
L
G
R
G
G
S
G
G
G
G
G
P
P
A
K
R
R
L
E
L
G
E
S
G
H
Q
Y
L
S
D
G
L
K
T
P
K
G
K
G
R
A
A
L
R
S
P
D
S
P
K
T
P
K
S
P
S
A
G
S
L
L
Y
T
T
P
H
G
P
S
S
R
A
G
L
L
Q
Q
P
P
A
L
G
R
G
G
S
G
G
G
G
G
P
P
A
K
R
R
L
E
L
G
E
S
G
H
Q
Y
L
S
D
G
L
K
T
P
K
G
K
G
R
A
A
L
R
S
P
D
S
P
K
T
P
K
S
P
S
A
G
S
L
I
Y
T
T
P
H
G
P
S
G
R
A
G
L
L
Q
Q
P
P
A
L
G
R
G
G
S
G
G
G
G
G
P
P
A
K
R
R
L
E
L
G
E
S
G
Q
Q
Y
L
S
D
G
L
K
T
P
K
G
K
G
R
A
A
L
R
S
P
D
S
P
K
T
P
K
S
P
S
A
S
S
L
-
Y
T
T
P
Q
G
P
S
S
R
V
G
L
L
Q
Q
P
P
A
P
G
R
G
G
-
-
-
G
G
G
P
P
A
K
R
R
L
E
L
G
E
S
G
H
Q
Y
L
S
D
G
L
K
T
P
K
G
K
G
R
A
A
L
R
S
P
D
S
P
K
T
P
K
S
P
S
A
G
S
L
L
Y
S
T
P
H
G
P
S
S
R
A
G
L
L
Q
Q
Q
P
A
L
G
R
G
G
-
-
-
G
G
G
P
P
A
K
R
R
L
E
L
G
E
S
G
H
Q
F
L
S
D
G
L
K
T
P
K
G
K
G
R
A
A
V
R
S
P
D
S
P
K
T
P
K
S
P
S
A
A
S
F
I
Y
S
T
P
H
G
P
A
T
R
A
G
Q
L
Q
-
-
P
A
L
G
R
-
-
-
-
-
-
-
-
P
P
A
K
R
R
L
E
L
G
D
G
S
H
Q
Y
L
S
D
G
L
K
T
P
K
G
K
G
R
A
V
T
H
C
P
D
S
P
K
T
P
K
S
P
L
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
R
G
G
G
G
G
G
G
G
F
P
A
K
R
R
L
E
L
G
E
S
G
H
Q
Y
L
A
E
G
L
K
T
P
K
G
K
G
R
A
A
T
R
S
P
D
S
P
K
T
P
K
S
P
S
S
A
D
S
L
Y
T
T
P
L
Q
G
S
T
H
G
T
G
L
R
-
-
P
T
L
G
R
-
-
-
-
-
-
-
-
P
P
A
K
R
R
L
E
L
D
I
T
D
H
Q
Y
S
E
P
A
K
T
L
R
S
R
K
G
-
-
-
A
L
K
L
K
I
P
K
A
P
K
T
P
P
N
T
A
Q
V
K
R
K
L
E
L
Q
S
S
S
S
G
S
M
N
S
Y
-
-
-
-
-
-
-
-
-
-
L
M
S
E
S
Q
I
Q
Q
L
Q
T
Q
N
F
V
N
N
Y
N
K
P
p
f
K
S
P
L
K
R
A
K
S
v
k
V
L
A
T
N
P
P
S
R
k
s
P
S
-
-
-
-
-
M
E
D
S
Y
N
D
M
E
D
P
G
F
R
Q
L
S
D
M
E
L
Q
K
A
L
E
M
T
K
Q
S
S
I
K
N
N
L
M
L
g
d
N
E
L
D
F
D
F
D
F
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
D
E
D
E
D
L
D
Q
P
Q
In isoform 2.
In isoform 2.
Transcription factor E2F3
DNA-binding region
Cyclin A/CDK2 binding
Poly-Gly
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

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