Myc box-dependent-interacting protein 1 (BIN1)
AlignmentMotifsModificationSwitchesStructureMutationIsoformsSNPsFeaturesDisorder

 
|351
|401
|430
LLDLD
K
E
V
K
Q
E
Q
I
L
S
L
F
E
D
T
F
V
P
E
I
S
V
T
T
P
S
Q
F
E
A
P
G
P
F
S
E
Q
A
S
L
L
D
L
D
F
D
P
L
P
P
V
T
S
P
V
K
A
P
T
P
S
G
Q
S
I
P
W
D
L
W
E
P
T
E
S
P
A
G
S
L
K
E
V
K
Q
E
Q
I
L
S
L
F
E
D
T
F
V
P
E
I
S
V
T
T
P
S
Q
F
E
A
P
G
P
F
S
E
Q
A
S
L
L
D
L
D
F
D
P
L
P
P
V
T
S
P
V
K
A
P
T
P
S
G
Q
S
I
P
W
D
L
W
E
P
T
E
S
P
A
G
S
L
K
E
V
K
Q
E
Q
I
L
S
L
F
E
D
T
F
V
P
E
I
S
V
T
T
P
S
Q
F
E
A
P
G
P
F
S
E
Q
A
S
L
L
D
L
D
F
D
P
L
P
P
V
T
S
P
V
K
A
P
T
P
S
G
Q
S
I
P
W
D
L
W
E
P
T
E
S
P
A
G
S
L
K
E
V
K
Q
E
Q
I
L
S
L
F
D
D
T
F
V
P
E
I
S
V
T
T
P
S
Q
F
E
A
P
G
P
F
S
E
Q
A
S
L
L
D
L
D
F
D
P
L
P
P
V
A
S
P
V
K
A
P
T
P
S
G
Q
S
I
P
W
D
L
W
E
P
T
E
S
P
A
G
S
L
K
E
M
K
Q
E
Q
I
L
S
L
F
D
D
A
F
V
P
E
I
S
V
T
T
P
S
Q
F
E
A
P
G
P
F
S
E
Q
A
S
L
L
D
L
D
F
E
P
L
P
P
V
A
S
P
V
K
A
P
T
P
S
G
Q
S
I
P
W
D
L
W
E
P
T
E
S
Q
A
G
I
L
K
E
I
K
Q
E
H
I
I
S
L
F
D
D
N
F
V
P
E
I
S
V
T
T
P
S
Q
F
D
A
P
G
P
F
Q
E
N
A
S
L
L
D
L
D
F
D
P
I
P
P
V
A
S
P
V
K
A
P
T
P
S
G
Q
S
I
P
W
D
L
W
E
A
A
E
S
P
A
G
S
L
K
D
F
K
Q
E
N
I
L
S
L
F
D
D
S
F
V
P
E
I
S
V
T
T
P
S
Q
F
E
V
T
W
P
Q
T
E
E
P
S
L
L
D
L
D
F
D
P
L
K
P
D
S
S
-
-
T
G
A
S
A
G
A
Q
S
L
P
W
D
L
W
e
p
L
A
E
K
S
S
S
G
K
E
I
K
Q
E
N
I
I
S
L
F
D
D
N
F
V
P
E
I
S
V
T
T
P
S
Q
F
D
A
P
G
P
F
Q
E
G
A
S
L
L
D
L
D
F
D
P
I
K
P
D
A
T
M
G
K
T
P
T
P
A
S
Q
S
L
P
W
D
L
W
E
S
T
K
N
P
A
G
S
-
K
S
L
E
R
P
E
L
S
G
L
N
A
S
A
K
A
T
T
T
T
Q
T
S
P
T
E
D
K
a
v
K
P
S
E
T
E
G
A
A
V
A
A
S
V
T
P
A
P
P
A
T
P
A
q
n
G
N
n
k
E
G
G
K
Q
P
K
E
L
P
-
S
T
T
S
N
A
E
A
A
R
D
H
E
R
S
K
S
Q
D
I
n
e
H
S
Y
E
K
S
H
e
q
R
K
P
R
S
N
S
D
K
-
-
-
-
T
S
H
Q
Y
V
N
L
E
I
G
K
S
P
D
G
K
T
K
I
S
D
P
V
N
N
G
D
G
-
-
-
-
-
-
-
P
S
V
Y
T
D
V
A
I
S
V
V
S
M
A
N
S
T
N
P
F
D
D
D
D
A
E
H
D
K
E
A
T
P
T
D
V
E
E
K
-
-
-
-
-
-
-
-
-
-
-
F
E
A
K
V
Y
P
K
L
N
A
Q
Q
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
A
N
S
-
-
-
-
-
-
-
-
-
-
-
N
D
N
S
L
N
N
Q
D
A
S
P
Q
N
T
V
T
A
S
K
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
In isoform BIN1-10-13 and isoform BIN1-13.
In isoform II3 and isoform BIN1.
In isoform IIC1 and isoform IIC2.
In isoform IID.
In isoform II2 and isoform BIN1+12A.
In isoform IIB.
Myc box-dependent-interacting protein 1
Clathrin-binding
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Powered by ProViz
hover over features for details